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− | == Introduction == | + | == Introduction == |
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− | *Contagious Bovine Pleuropneumonia (CBPP) is a respiratory disease of cattle. It is notifiable in the UK and many other countries and has not been seen here for many years. It is transmitted by close contact with clinically or subclinically affected animals and severity depends on strain and host susceptibilit. There is usually around a 50% morbidity and high mortality rate in severe outbreaks.<br> | + | *Contagious Bovine Pleuropneumonia (CBPP) is a respiratory disease of cattle. It is notifiable in the UK and many other countries and has not been seen here for many years. It is transmitted by close contact with clinically or subclinically affected animals and severity depends on strain and host susceptibility. There is usually around a 50% morbidity and high mortality rate in severe outbreaks.<br> |
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| + | == Clinical signs == |
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| + | Clinical signs include an acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal dischargewhich all occur suddenly. Dyspnoea occurs with abducted elbows and extended necks and an expiratory grun. The disease can be fatal within 1-3 week. |
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− | == Clinical signs == | + | Calves may suffer from [[Infectious Arthritis#In_Cattle|arthritis]], synovitis and endocarditis, but are most commonly seen as sudden death. |
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| + | == Diagnosis == |
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| + | Clinical signs and history to suspect diagnosis but definative diagnosis should be achived by post mortem examination. Signs at necropsy will include marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas, serofibrinous pleural fluidand necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection. |
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| + | A PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage of fluids useful, as is fluorescent antibody testor serological tests such as serum agglutination, haemagglutination, complement fixation and ELIS. Due to the rareity of the disease in developed countries, the best diagnostic tool is not known.<br> |
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− | Clinical signs include an acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal dischargewhich all occur suddenly. Dyspnoea occurs with abducted elbows and extended necks and an expiratory grun. The disease can be fatal within 1-3 week.
| + | == Treatment and control == |
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− | Calves may suffer from [[Infectious Arthritis#In_Cattle|arthritis]], synovitis and endocarditi, but are most commonly seen as sudden death.
| + | Slaughter of affected cattle in countries where the disease is exoticis neccessary by law. Movement restrictions, quarantene and slaughter of carrier animals in endemic countries is required. Vaccination has been used in endemic regions. |
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| + | == References<br> == |
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− | == Diagnosis ==
| + | Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) Bovine Medicine (Second edition), Blackwell Publishing<br> |
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− | Clinical signs and history to suspect diagnosis but definative diagnosis should be achived by post mortem examination. Signs at necropsy will include marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas
| + | Radostits, O.M, Arundel, J.H, and Gay, C.C. (2000) Veterinary Medicine: a textbook of the diseases of cattle, sheep, pigs, goats and horses Elsevier Health Sciences<br> |
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− | *Serofibrinous pleural fluid
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− | *Necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection
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− | *Diagnosis
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− | **Clinical signs and post-mortem appearance
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− | **PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
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− | **Fluorescent antibody test
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− | **Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
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− | *Treatment and control
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− | **Slaughter of affected cattle in counries where the disease is exotic
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− | **Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
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− | *''M. mycoides'' subsp. 'mycoides''causes septicaemia, pleuropneumonia, arthritis and mastitis in goats''
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− | **Vaccination in endemic regions
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− | *Caused by [[Mycoplasma mycoides subsp. mycoides|''Mycoplasma mycoides'']], small colony variant
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− | *Causes a fibrinonecrotic [[Pneumonia Overview#Infectious_causes_of_pneumonia|pneumonia]] and [[Pleuritis|fibrinous pleuritis]]
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− | *Also affects caudodorsal areas
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− | *[[Bronchopneumonia|Bronchopneumonia]] -> [[Lobar Pneumonia|lobar pneumonia]]
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− | *Sequestra are common
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− | *NB: similarity to pneumonic pasteurellosis but CBPP has more pronounced marbled effect
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− | *Interstitial septa are markedly widened by fibrinous exudate and the necrotic areas may have a fibrous capsule
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− | *Large colony variant will cause a similar disease in goats
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− | [[Category:Respiratory_Diseases_-_Cattle]] [[Category:To_Do_-_Kate]] [[Category:Respiratory_Bacterial_Infections]] | + | [[Category:Respiratory_Diseases_-_Cattle]] [[Category:To_Do_-_Review]] [[Category:Respiratory_Bacterial_Infections]] |