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== Introduction<br> ==

== Introduction ==

This is a rare syndrome is a complex of&nbsp; Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.<br>

This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.

Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease. <br>

Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.  

== Clinical Signs<br> ==

== Clinical Signs ==

Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, stomatitis, gingivitis and glossitis are all possible clinical signs.<br>

Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[gingivitis]] and [[glossitis]] are all possible clinical signs.

== Diagnosis<br> ==

== Diagnosis ==

Diagnosis by elimination of all other causes of these clinical signs.<br>

Diagnosis by elimination of all other causes of these clinical signs.

== Treatment<br> ==

== Treatment ==

None.<br>

None

Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.<br>

Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.

== Prognosis<br> ==

== Prognosis ==

Guarded to Poor<br>

Guarded to Poor

== References<br> ==

== References ==

Merck &amp; Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial<br>Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier. <br>Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams &amp; Wilkins. <br><br>

Merck &amp; Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial

[[Category:Salivary_Glands_-_Pathology]] [[Category:To_Do_-_Review]]

 

 

 

[[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]]