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Created page with "{{Template:Manson}} centre|500px <br /> '''A 6-year-old Holstein cow, which calved 36 hr earlier, is presented in sternal recumbency, profound..."
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'''A 6-year-old Holstein cow, which calved 36 hr earlier, is presented in sternal recumbency, profoundly depressed, dehydrated, afebrile (38.5°C,101.3°F)), with toxic mucous membranes, an elevated heart rate of 96 beats per minute, and an increased respiratory rate (34 breaths per minute). The udder is soft but a pale, serum-like, secretion can be drawn from one quarter.'''

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<FlashCard questions="3">
|q1=Which diseases would you consider? (Most likely first.)
|a1=
The most likely conditions to consider include:
*environmental (coliform) mastitis
*hypocalcaemia
*acute septic metritis
*other infectious conditions causing toxaemia/endotoxaemia
*trauma at parturition with either ruptured uterus/peritonitis or severe haemorrhage
*botulism <br><br>
It may prove difficult to rule out the possible contribution of hypocalcaemia and many clinicians would elect to administer 400 mL of 40% calcium borogluconate slowly by the intravenous route while monitoring the heart rate.
|l1=Streptococcal mastitis - bovine
|q2=What treatments would you administer?
|a2=
Treatment of endotoxic shock (coliform mastitis) includes intravenous injection of a NSAID, repeated 12 hr later. <br><br>
Hypertonic saline (7.2%) infusion at a dose rate of 5mL/kg (3 L for 600 kg cow) over 5–7 minutes is achieved through a 13-gauge 10cm jugular catheter. <br><br>
Access to 30–60 L of warm water, which may contain electrolytes, must be provided although not all cows drink; some clinicians recommend stomach tubing volumes up to 30–40 L. <br><br>
This cow made a full recovery. Mastitis caused by ''Streptococcus uberis'' can present with many of the clinical features of coliform mastitis and it may prove prudent to administer a broad-spectrum antibiotic both parenterally and by intramammary infusion.
|l2=
|q3=What control measures could be adopted?
|a3=
*Control measures include proper hygiene in the calving accommodation.
*Premilking teat dipping should be included in the parlour routine.
*Cows should be kept standing for 30 minutes after milking to enable complete teat sphincter contraction.
*Teat sealants should be used at drying-off.
*Use of J5 ''Escherichia coli'' core antigen vaccine could be considered.
|l3=
</FlashCard>

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