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Bone Response to Damage (view source)
Revision as of 08:55, 10 October 2007
, 08:55, 10 October 2007no edit summary
===Periosteum and blood supply===
===Periosteum and blood supply===
*Specialised sheath of connective tissue covering bone except at the articular surfaces
*Periosteum
*Inner layer
**Specialised sheath of connective tissue covering bone except at the articular surfaces
**Merges with the outer layer of bone
**Loosely attached except at tendon insertions and boney prominences (associated with major blood vessels penetrating bone)
**Contains osteoblasts and osteoprogenitor stem cells in young animals and in adults with fractures or disease
**Histologically:
*Damage to the periosteum invokes a hyperplastic reaction of the inner layer
***Outer layer - fibrous for support
*The blood supply to the mature bone enters via the periosteum
***Inner layer - osteogenic
****Contains osteoblasts and osteoprogenitor stem cells in young animals and in adults with fractures or disease
**Rich supply of nerves and lymph vessels
**Damage to the periosteum invokes a hyperplastic reaction of the inner layer
*Blood vessels
**Nutrient, metaphyseal, periosteal arteries
**Normal flow of blood from medulla to periosteum due to higher pressures in medulla
**Young animals have greater blood supply
*'''Endosteum''' lines the marrow cavity
*'''Endosteum''' lines the marrow cavity