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==Introduction==
 
==Introduction==
Blue eye disease is caused by the virus [[Blue-Eye Paramyxovirus|'''''Blue-eye paramyxovirus (BEP)''''']]. It casues '''nervous, reproductive''' and '''respiratory signs''' in its domestic host, the pig. The disease is not considered a zoonosis.
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Blue eye disease is caused by the virus [[Blue-Eye Paramyxovirus|'''''Blue-eye paramyxovirus (BEP)''''']]. It causes '''nervous, reproductive''' and '''respiratory signs''' in its domestic host, the pig. The disease is not considered a zoonosis.
    
==Signalment==
 
==Signalment==
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==Clinical Signs==
 
==Clinical Signs==
'''Generally''' pigs suffer from '''anorexia''', weight loss, '''reluctance to move''', dehydration, periorbital and conjunctival swelling (chemosis) and '''purulent/serous occular discharge''' and '''corneal opacity'''.  The virus also causes neurological signs including tetraparesis, opisthotonus, dysmetria, proprioceptive disorders, '''tremors''', nystagmus   
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'''Generally''' pigs suffer from '''anorexia''', weight loss, '''reluctance to move''', dehydration, periorbital and conjunctival swelling (chemosis) and '''purulent/serous ocular discharge''' and '''corneal opacity'''.  The virus also causes neurological signs including tetraparesis, opisthotonus, dysmetria, proprioceptive disorders, '''tremors''', nystagmus   
 
mydriasis, blindness, decreased or absent menace response and respiratory signs; tachypnea, dyspnea, and '''open mouthed breathing'''.
 
mydriasis, blindness, decreased or absent menace response and respiratory signs; tachypnea, dyspnea, and '''open mouthed breathing'''.
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'''Piglets and Weaners:'''
 
'''Piglets and Weaners:'''
Piglet and weaners suffer from prostration, hind limb '''stiffness''', generalised weakness, muscle facsiculations, retarded growth, depression, excitation, head pressing, circling, '''hyperaesthesia''', abnormal behaviour/'''aggression''' and '''coma'''. In piglets the disease also causes '''changes in hair coat''' (dull/rough), '''occular erosions''', '''enlarged distended bladder''' and  '''constipation/reduction in faces or diarrhoea'''.
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Piglet and weaners suffer from prostration, hind limb '''stiffness''', generalised weakness, muscle fasciculation’s, retarded growth, depression, excitation, head pressing, circling, '''hyperaesthesia''', abnormal behaviour/'''aggression''' and '''coma'''. In piglets the disease also causes '''changes in hair coat''' (dull/rough), '''ocular erosions''', '''enlarged distended bladder''' and  '''constipation/reduction in faces or diarrhoea'''.
    
'''Sows'''
 
'''Sows'''
In sows the disease causess '''infertility''', reproductive failures, '''embryonic mortality''' and '''return to oestrus in the first third of gestation''' and '''stillbirths, small litters''' and '''mummification in late gestation'''.  
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In sows the disease causes '''infertility''', reproductive failures, '''embryonic mortality''' and '''return to oestrus in the first third of gestation''' and '''stillbirths, small litters''' and '''mummification in late gestation'''.  
    
'''Boar'''
 
'''Boar'''
In the boar it casues male '''infertility, lack of libido, haemospermia''', and '''orchitis with epidydimitis''' and swelling of the genitals.
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In the boar it causes male '''infertility, lack of libido, haemospermia''', and '''orchitis with epidydimitis''' and swelling of the genitals.
    
==Epidemiology==
 
==Epidemiology==
The disease is '''self limited''' and closed herds will have sporadic outbreaks of the disease once a herd is infected. The virus can be found in the '''axon of neurons''' from it's original site of replication, which is thought to be the '''nasal mucosa and tonsils'''.  It is also found in tissues such as lung, liver, spleen, kidney, lymph node, heart and testis; suggesting that the virus is spread hematogenously.
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The disease is '''self limited''' and closed herds will have sporadic outbreaks of the disease once a herd is infected. The virus can be found in the '''axon of neurons''' from its original site of replication, which is thought to be the '''nasal mucosa and tonsils'''.  It is also found   in tissues such as lung, liver, spleen, kidney, lymph node, heart and testis; suggesting that the virus is spread hematogenously.
    
==Distribution==
 
==Distribution==
The disease is economically important to '''Central Mexico and it's states'''.
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The disease is economically important to '''Central Mexico and its states'''.
    
==Diagnosis==
 
==Diagnosis==
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During infection '''lymphocytosis''' and '''monocytosis''' may be observed.
 
During infection '''lymphocytosis''' and '''monocytosis''' may be observed.
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On '''post mortem''' all age ranges have corneal opacity which is mainly unilateral.  Piglets show evidence of mild pneumonia, distended bladder and stomach, fibrin strands in the peritoneal cavity and '''congestion in the brain'''.  Growers show kidney and '''pericardial haemorrhages''' aswell as brain congestion. '''Necrosis of the seminiferous tubules''' and rupture of the epidydimis walls and subsequent abscess and granuloma formation has been documented in boars.
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On '''post mortem''' all age ranges have corneal opacity which is mainly unilateral.  Piglets show evidence of mild pneumonia, distended bladder and stomach, fibrin strands in the peritoneal cavity and '''congestion in the brain'''.  Growers show kidney and '''pericardial haemorrhages''' as well as brain congestion. '''Necrosis of the seminiferous tubules''' and rupture of the epidydimis walls and subsequent abscess and granuloma formation has been documented in boars.
    
'''Differential diagnosis''':PRRS and Pseudorabies.
 
'''Differential diagnosis''':PRRS and Pseudorabies.
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