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Chicken Anaemia Virus Disease Flashcards (view source)
Revision as of 10:54, 29 June 2011
, 10:54, 29 June 2011no edit summary
|q1=What is Chicken Anaemia Virus Disease also commonly known as?
|q1=What is Chicken Anaemia Virus Disease also commonly known as?
|a1=
|a1=
*Chicken anaemia
*''Chicken anaemia''
*Chicken infectious anaemia
*''Chicken infectious anaemia''
*Blue wing disease
*''Blue wing disease''
|l1=Chicken Anaemia Virus Disease#Introduction
|l1=Chicken Anaemia Virus Disease#Introduction
|q2=Which virus causes ''Chicken Anaemia Virus Disease'' and what are it's properties?
|q2=Which virus causes ''Chicken Anaemia Virus Disease'' and what are it's properties?
|l2=Chicken Anaemia Virus Disease#Introduction
|l2=Chicken Anaemia Virus Disease#Introduction
|q3=What family does the ''Chicken anaemia virus'' (CAV) belong to?
|q3=What family does the ''Chicken anaemia virus'' (CAV) belong to?
|a3=Circoviridae
|a3=''Circoviridae''
|l3=Chicken Anaemia Virus Disease#Introduction
|l3=Chicken Anaemia Virus Disease#Introduction
|q4=What chemicals destroy the virus?
|q4=What chemicals destroy the virus?
|a4=
|a4=
*Hypochlorite and iodophor (Formalin only reduces its infectivity).
*Hypochlorite and iodophor (formalin only reduces its infectivity).
|l4=Chicken Anaemia Virus Disease#Introduction
|l4=Chicken Anaemia Virus Disease#Introduction
|q5=How many proteins does CAV produce?
|q5=How many proteins does CAV produce?
*VP1 (52kDA) - structural protein; intracellular form of the capsid protein
*VP1 (52kDA) - structural protein; intracellular form of the capsid protein
*VP2 (24 kDA) - found in small amounts in the purified virus
*VP2 (24 kDA) - found in small amounts in the purified virus
*VP3 (14 kDA) - involved in apoptosis (programmed and controlled cell death with no lysis of the cell. Causes apoptosis of infected stem cells in the bone marrow (BM). Sequential damage to BM inhibits the production of red blood cells (RBC), white blood cells (WBC), lymphoid tissue and platelets
*VP3 (14 kDA) - involved in apoptosis (programmed and controlled cell death with no lysis of the cell. Causes apoptosis of infected stem cells in the bone marrow (BM). Sequential damage to BM inhibits the production of red blood cells (RBC), white blood cells (WBC), lymphoid tissue and platelets.
Vaccines need to contain both VP1 and VP2 to be antigenic.
Vaccines need to contain both VP1 and VP2 to be antigenic.
|q7=What species of birds does the CAV infect?
|q7=What species of birds does the CAV infect?
|a7=
|a7=
*Chickens (but can also affect quail).
*Chickens (but can also affect quail). The disease severely affects 10-14 day old chicks.
The disease is more severe in chicks.
|l7=Chicken Anaemia Virus Disease#Signalment
|l7=Chicken Anaemia Virus Disease#Signalment
|q8=What are the clinical signs of Chicken Anaemia Virus Disease?
|q8=What are the clinical signs of Chicken Anaemia Virus Disease?
|a8=
|a8=
*Clinical signs are dependent on the age of the bird.
*Clinical signs are dependent on the age of the bird.
*Chicks develop clinical signs within two weeks of hatching if infected via vertical transmission. *Chicks older than 14 days old do not show any clinical signs if infected via horizontal transmission.
*Chicks develop clinical signs within two weeks of hatching if infected via vertical transmission.
*Chicks older than 14 days old do not show any clinical signs if infected via horizontal transmission.
Clinical signs include:
Clinical signs include:
*Cyanosis, petechiation and ecchymoses,
*Cyanosis, petechiation and ecchymoses,
*Weakness, lethargy and sudden death.
*Weakness, lethargy and sudden death.
Neurological signs include:
Neurological signs include: