Although the above image is of a relatively poor quality, it is useful in displaying the general histologic appearence of the cerebellum. This cerebellum has been stained with haematoxylin and eosin (H&E) and shows the outermost '''molecular layer''' and the inner '''granular layer'''. The molecular layer stains more intensely with eosin whilst the granular layer stains more intensely with haematoxylin. Both of these layers make up the cortex of the cerebellum. Although not visible on this image, the granular layer contains a further, deeper area that stains less intensely with haematoxylin. This lighter central contains the white matter. In this image there is a moderate degree of detachment of the molecular layer from the granular layer which is due to the histology fixing process rather than the true physiological appearance.
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On the outer edge of the molecular layer it is possible to visualise the pia mater fibrous covering. In the above image and as is common in cerebellar histology, the fixing process causes shrinkage of the pia mater resulting in an artefact appearance.