Changes

This occurs following a direct insult to the kidney from several possible causes including:  

This occurs following a direct insult to the kidney from several possible causes including:  

*'''Exogenous toxins''' including heavy metals, [[Aminoglycosides|aminoglycosides]], [[Tetracyclines|tetracyclines]], polymixin B, cisplatin, antifreeze ([[Ethylene Glycol Toxicity|ethylene glycol]]), lilies in cats and grapes in dogs.  

*'''Exogenous toxins''' including heavy metals, [[Aminoglycosides|aminoglycosides]], [[Tetracyclines|tetracyclines]], polymixin B, cisplatin, antifreeze ([[Ethylene Glycol Toxicity|ethylene glycol]]), NSAIDs, lilies in cats and grapes in dogs.  

*'''Endogenous toxins''' including haemoglobin, myoglobin and calcium.  

*'''Endogenous toxins''' including haemoglobin, myoglobin and calcium.  

*Infections such as '''pyelonephritis''', '''interstitial nephritis''' (as caused by [[Leptospirosis - Cats and Dogs|''Leptospira spp.'']] or '''granulomatous nephritis''' (as caused by the dry form of [[Feline Infectious Peritonitis]]).  

*Infections such as '''pyelonephritis''', '''interstitial nephritis''' (as caused by [[Leptospirosis - Cats and Dogs|''Leptospira spp.'']] or '''granulomatous nephritis''' (as caused by the dry form of [[Feline Infectious Peritonitis]]).