Changes

==Prognosis==

==Prognosis==

===Cats and Dogs===

===Cats and Dogs===

The mean survival times for dogs and cats without therapy is 6-8 weeks. For those receiving corticosteroids alone is 3 months.

The mean survival times for dogs and cats without therapy is 6-8 weeks. For those receiving corticosteroids alone it is thought to be around 3 months.

If chemotherapy is administered then the mean survival time increases to 6-9 months.

If chemotherapy is administered then the mean survival time increases to 6-12 months for canine multicentric lymphoma depending on the protocol used and a huge variety of other factors - the median survival of other disease sites and species is less well documented. Documented poor prognostic indicators in the dog include T cell immunophenotype, cranial mediastinal involvement, hypercalcemia, bone marrow involvement and being ill at diagnosis (substage b).  

Local canine lymphoma responds better to chemotherapy than the diffuse form of disease.  

Local canine lymphoma responds better to chemotherapy than the diffuse form of disease.  

Immunophenotype (T cell versus B cell lymphoma) does not appear to be associated with prognosis in cats as it can be in dogs. Factors indicating a better prognosis (overall survival) in '''cats''' include: '''an early presentation, a complete initial response to treatment and a clinically well patient''' (‘substage a’ disease).

Immunophenotype (T cell versus B cell lymphoma) does not appear to be associated with prognosis in cats as it can be in dogs. Factors indicating a better prognosis (overall survival) in '''cats''' include: '''an early presentation, a complete initial response to treatment and a clinically well patient''' (‘substage a’ disease).