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==<font color="purple">Immune tolerance</font>==
 
==<font color="purple">Immune tolerance</font>==
{| border="3" cellpadding="8"
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<FlashCard questions="10">
!width="400"|'''Question'''
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|q1=What is the definition of tolerance?
!width="400"|'''Answer'''
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|a1=A state of immune unresponsiveness towards antigens
!width="150"|'''Article'''
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|l1=Immune Tolerance
|-
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|q2=Where does central tolerance develop?
|<big>'''What is the definition of tolerance?'''
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|a2=Thymus
||<font color="white"> <big>
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|l2=Immune Tolerance
*'''''A state of immune unresponsiveness towards antigens'''''
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|q3=What are the two processes of selection known as?
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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|a3=
|-
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*Positive selection
|<big>'''Where does central tolerance develop?'''
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*Negative selection
||<font color="white"> <big>
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|l3=Immune Tolerance
*'''''Thymus'''''
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|q4=What are the four ways peripheral tolerance can be achieved in T cells?
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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|a4=
|-
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*Ignorance
|<big>'''What are the two processes of selection known as?'''
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*Anergy
||<font color="white"> <big>
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*Cell death
*'''''Positive selection'''''
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*Immune deviation/suppression
*'''''Negative selection'''''
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|l4=Immune Tolerance
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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|q5=What is the process in which one T cell response is selectively induced over another?
|-
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|a5=Immune deviation
|<big>'''What are the four ways peripheral tolerance can be achieved in T cells?'''
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|l5=Immune Tolerance
||<font color="white"> <big>
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|q6='''What subtype are regulatory T cells?
*'''''Ignorance'''''
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|a6=CD4+
*'''''Anergy'''''
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|l6=Immune Tolerance
*'''''Cell death'''''
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|q7=What part of the body do Treg cells develop?
*'''''Immune deviation/suppression'''''
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|a7=Thymus
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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|l7=Immune Tolerance
|-
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|q8=What typical inhibitory cytokines do Treg cells secrete?
|<big>'''What is the process in which one T cell response is selectively induced over another?'''
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|a8=
||<font color="white"> <big>
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*IL-4
*'''''Immune deviation'''''
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*IL-10
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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*TGF-β
|-
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|l8=Immune Tolerance
|<big>'''What is the definition of tolerance?'''
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|q9=The mechanism of suppression of Treg cells depends on the binding of which receptors?
||<font color="white"> <big>
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|a9=Treg CTLA-4 to target cell B7
*'''''A state of immune unresponsiveness towards antigens'''''
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|l9=Immune Tolerance
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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|q10=What is the transcription repressor unique to Treg cells?
|-
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|a10=FoxP3
|<big>'''What subtype are regulatory T cells?'''
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|l10=Immune Tolerance
||<font color="white"> <big>
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</FlashCard>
*'''''CD4+'''''
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||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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<br><br>
|-
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{{Jim Bee 2007}}
|<big>'''What part of the body do Treg cells develop?'''
  −
||<font color="white"> <big>
  −
*'''''Thymus'''''
  −
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
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|-
  −
|<big>'''What typical inhibitory cytokines do Treg cells secrete?'''
  −
||<font color="white"> <big>
  −
*'''''IL-4'''''
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*'''''IL-10'''''
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*'''''TGF-β'''''
  −
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''The mechanism of suppression of Treg cells depends on the binding of which receptors?'''
  −
||<font color="white"> <big>
  −
*'''''Treg CTLA-4 to target cell B7'''''
  −
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What is the transcription repressor unique to Treg cells?'''
  −
||<font color="white"> <big>
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*'''''FoxP3'''''
  −
||[[Immune Tolerance|<span title="Answer article">Link to Answer Article</span>]]
  −
|}
   
[[Category:Immunology Flashcards]]
 
[[Category:Immunology Flashcards]]
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