Immune Tolerance Flashcards
Jump to navigation
Jump to search
Immune tolerance
| Question | Answer | Article | |
| What is the definition of tolerance? | A state of immune unresponsiveness towards antigens
|
Link to Article | |
| Where does central tolerance develop? | Thymus
|
Link to Article | |
| What are the two processes of selection known as? |
|
Link to Article | |
| What are the four ways peripheral tolerance can be achieved in T cells? |
|
Link to Article | |
| What is the process in which one T cell response is selectively induced over another? | Immune deviation
|
Link to Article | |
| What subtype are regulatory T cells? | CD4+
|
Link to Article | |
| What part of the body do Treg cells develop? | Thymus
|
Link to Article | |
| What typical inhibitory cytokines do Treg cells secrete? |
|
Link to Article | |
| The mechanism of suppression of Treg cells depends on the binding of which receptors? | Treg CTLA-4 to target cell B7
|
Link to Article | |
| What is the transcription repressor unique to Treg cells? | FoxP3
|
Link to Article | |
|
Originally funded by the RVC Jim Bee Award 2007 |