Immune Tolerance Flashcards
Immune tolerance
| Question | Answer | Article | |
| What is the definition of tolerance? | A state of immune unresponsiveness towards antigens
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Link to Article | |
| Where does central tolerance develop? | Thymus
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Link to Article | |
| What are the two processes of selection known as? |
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Link to Article | |
| What are the four ways peripheral tolerance can be achieved in T cells? |
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Link to Article | |
| What is the process in which one T cell response is selectively induced over another? | Immune deviation
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Link to Article | |
| What subtype are regulatory T cells? | CD4+
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Link to Article | |
| What part of the body do Treg cells develop? | Thymus
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Link to Article | |
| What typical inhibitory cytokines do Treg cells secrete? |
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Link to Article | |
| The mechanism of suppression of Treg cells depends on the binding of which receptors? | Treg CTLA-4 to target cell B7
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Link to Article | |
| What is the transcription repressor unique to Treg cells? | FoxP3
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Link to Article | |
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Originally funded by the RVC Jim Bee Award 2007 |