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→Classical Pathway
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The main action of the C3b molecule is to form the C4b¯2a¯3b complex, or the '''C5 convertase (classical pathway)'''. The C5 convertase then activates C5 and initiates the [[#Membrane Attack Complex|membrane attack complex]] (MAC) as shown below. Other actions include the fragmentation of the C3b due to the actions of [[#Factors I and H|Factors I and H]] which forms C3bi, which provides an opsonin for [[Phagocytosis|phagocytosis]].
The main action of the C3b molecule is to form the C4b¯2a¯3b complex, or the '''C5 convertase (classical pathway)'''. The C5 convertase then activates C5 and initiates the [[#Membrane Attack Complex|membrane attack complex]] (MAC) as shown below. Other actions include the fragmentation of the C3b due to the actions of [[#Factors I and H|Factors I and H]] which forms C3bi (C3bi and iC3b are the same protein, different name), which provides an opsonin for [[Phagocytosis|phagocytosis]].
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