Changes

<p>Neutrophils do not always destroy engulfed particles and may instead transport them to local lymph nodes to be dealt with by other host defence mechanisms. This means that acute inflammation in tissue can be accompanied by an acute inflammation in the lymph nodes.</p>

<p>Neutrophils do not always destroy engulfed particles and may instead transport them to local lymph nodes to be dealt with by other host defence mechanisms. This means that acute inflammation in tissue can be accompanied by an acute inflammation in the lymph nodes.</p>

====Recognition====

====Recognition====

<p>To function correctly neutrophils need to correctly identify material that is either foreign (non-self) or which requires removal, such as damaged cells. They are able to recognise some foreign material directly but in other circumstances proteins (opsonins) that bind to bacteria are required to increase the chances of successfully binding the foreign material to the neutrophil.</p>

<p>To function correctly neutrophils need to correctly identify material that is either foreign (non-self) or which requires removal, such as damaged cells. They are able to recognise some foreign material directly but in other circumstances proteins (opsonins) that bind to bacteria are required to increase the chances of successfully binding the foreign material to the neutrophil. Some examples of opsonins include [[Complement|complement]] component C3bi and bound [[Immunoglobulins|antibody]].  </p>

 

====Killing====

====Killing====

<p>This occurs using either oxygen dependant pathways or oxygen independent pathways.</p>

<p>This occurs using either oxygen dependant pathways or oxygen independent pathways.</p>