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==Introduction==

==Introduction==

Neutrophils represent up to 70% of all [[Leukocytes|leukocytes]] in the blood stream and are distinguished by their irregular multi-lobed nucleus and indistinct granular appearance.  They are 10-12µm and circulate in the blood for minutes to hours (average 6-8 hours) and lasting for 1-2 days in tissue. Although the most abundant leukocyte in the blood the vast majority of neutrophils are found in the [[Bone Marrow - Anatomy & Physiology|bone marrow]] (5x more) mostly as functionally immature precursor cells, although this varies between species with mice having a large pool of functional neutrophils in their bone marrow. Neutrophils play a key role during bacterial infections and have both phagocytic and killing actions.

Neutrophils represent up to 70% of all [[Leukocytes|leukocytes]] in the blood stream (in humans there are 4.4 million neutrophils / millilitre of blood) and are distinguished by their irregular multi-lobed nucleus and indistinct granular appearance.  They are 10-12µm and circulate in the blood for minutes to hours (average 6-8 hours) and lasting for 1-2 days in tissue. Although the most abundant leukocyte in the blood the vast majority of neutrophils are found in the [[Bone Marrow - Anatomy & Physiology|bone marrow]] (5x more) mostly as functionally immature precursor cells, although this varies between species with mice having a large pool of functional neutrophils in their bone marrow. Neutrophils play a key role during bacterial infections and have both phagocytic and killing actions.

<p>Neutrophils are called '''[[Heterophils|heterophils]]''' in birds, reptiles and some mammals.</p>

<p>Neutrophils are called '''[[Heterophils|heterophils]]''' in birds, reptiles and some mammals.</p>