495
edits
Changes
Jump to navigation
Jump to search
→TH2 Cells
==TH<sub>2</sub> Cells==
==TH<sub>2</sub> Cells==
[[Image:TH2-Bcell.jpg|thumb|right|200px|TH2 cells incite increased antibody production - B. Catchpole, RVC 2008]]
[[Image:TH2-Bcell.jpg|thumb|right|200px|TH2 cells incite increased antibody production - B. Catchpole, RVC 2008]]
TH<sub>2</sub> cells help [[B cells]] produce antibody where the organism in present in tissue fluid. The TH2 population influences B cell activation, proliferation and immunoglobulin production. TH<sub>2</sub> T cells also secrete a range of cytokines:
TH<sub>2</sub> cells help [[B cells]] produce antibody where the organism in present in tissue fluid. The TH<sub>2</sub> population influences B cell activation, proliferation and immunoglobulin production. TH<sub>2</sub> T cells also secrete a range of cytokines:
#'''IL-4''' which stimulates B cell growth and induces the heavy chain switch from [[Immunoglobulin M|IgM]] to [[Immunoglobulin G|IgG]] , [[Immunoglobulin A|IgA]] and [[Immunoglobulin E|IgE]], as well as proliferation of basophils and mast cells. IL-4 can inhibit some T cell responses.
#'''IL-4''' which stimulates B cell growth and induces the heavy chain switch from [[Immunoglobulin M|IgM]] to [[Immunoglobulin G|IgG]] , [[Immunoglobulin A|IgA]] and [[Immunoglobulin E|IgE]], as well as proliferation of basophils and mast cells. IL-4 can inhibit some T cell responses.
#'''IL-5''' which activates B cells and stimulates a high rate of proliferation. IL-5 also promotes immunoglobulin synthesis and the proliferation and differentiation of eosinophils.
#'''IL-5''' which activates B cells and stimulates a high rate of proliferation. IL-5 also promotes immunoglobulin synthesis and the proliferation and differentiation of eosinophils.