==='''Degranulation of [[Mast Cells|mast cells]]/[[Eosinophils|eosinophils]]'''===
==='''Degranulation of [[Mast Cells|mast cells]]/[[Eosinophils|eosinophils]]'''===
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Antibodies play an important role in the [[Innate Immunity Cellular Responses|innate immune response]] to parasites. The Eosinophils and Mast Cells have FcR that are specific to IgE. When the IgE are cross-linked by antigen the eosinophils and Mast cells can interact with the IgE causing the release of their granules through the process known as exocytosis (granule fusion with the plasma membrane). The causes proteolytic enzyme release from eosinophils, and vasoactive peptide and cytokine release in mast cells which then activates the innate immune response.
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Antibodies play an important role in the [[Innate Immunity Cellular Responses|innate immune response]] to parasites. The Eosinophils and Mast Cells have FcR that are specific to IgE. When the IgE are cross-linked by antigen the eosinophils and Mast cells can interact with the IgE causing the release of their granules through the process known as exocytosis (granule fusion with the plasma membrane). The causes proteolytic enzyme release from eosinophils, and vasoactive peptide and cytokine release by Mast cells which then activates the innate immune response.