Cell-mediated immunity provides help for macrophages. It includes [[Immunoglobulin G|IgG]] production (T-helper type II (TH<sub>2</sub>) cells and [[Lymphocytes#B Cells|B cells]]), which improves phagocytosis by opsonisation. Infected [[Macrophages|macrophages]] are rescued by T-helper type I (TH<sub>1</sub>) cells when phagocytosis and digestion mechanisms fail to eliminate the pathogen.
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Cell-mediated immunity provides help for macrophages. It includes [[Immunoglobulin G|IgG]] production (through T-helper type II (TH<sub>2</sub>) cell interaction with [[Lymphocytes#B Cells|B cells]]), which improves phagocytosis by opsonisation. Infected [[Macrophages|macrophages]] are rescued by T-helper type I (TH<sub>1</sub>) cells when phagocytosis and digestion mechanisms fail to eliminate the pathogen.