Changes

==Introduction==

==Introduction==

Complement is so called because it complements the function of antibody. It is a [[Triggered Enzyme Cascade - WikiBlood|triggered enzyme cascade]] and there are more than 20 different proteins in the complement cascades, with most being enzymes or pro-enzymes. It can be activated by both the innate and adaptive immune systems and is one of the main innate protective mechanisms of invertebrates. Due to its destructive potential the complement system is heavily regulated but when activated it works largely by forming pore complexes as well as triggering acute inflammation and by promoting [[Phagocytosis|phagocytosis]] by [[Macrophages|macrophages]] and [[Neutrophils|neutrophils]].

Complement is so called because it complements the function of [[Immunoglobulins - Overview|antibody]]. It is a [[Triggered Enzyme Cascade|triggered enzyme cascade]] and there are more than 20 different proteins in the complement cascades, with most being enzymes or pro-enzymes. It can be activated by both the [[Innate Immune System|innate]] and [[Adaptive Immune System|adaptive]] immune systems and is one of the main innate protective mechanisms of invertebrates. Due to its destructive potential the complement system is heavily regulated but when activated it works largely by forming pore complexes as well as triggering [[Acute Inflammation - Introduction|acute inflammation]] and by promoting [[Phagocytosis|phagocytosis]] by [[Macrophages|macrophages]] and [[Neutrophils|neutrophils]].

 

==Complement Fixation Pathways==

==Complement Fixation Pathways==

[[Image:LH Complement pathway.png|thumb|left|250px|'''Classical and alternative pathways''']]

[[Image:LH Complement pathway.png|thumb|left|250px|'''Classical and alternative pathways''']]