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→5-HT3 Receptor Antagonists
===5-HT<sub>3</sub> Receptor Antagonists===
===5-HT<sub>3</sub> Receptor Antagonists===
[[File:Ondansetron skeletal.svg|200px|thumb|right|Skeletal formula of ondansetron. (<small>Sourced from Wikipedia.</small>]]
An example is '''ondansetron''', which works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre.
An example is '''ondansetron''', which works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting), often following chemotherapy. It affects both peripheral and central nerves. Ondansetron reduces the activity of the [[Vagus Nerve|vagus nerve]], which deactivates the vomiting center in the [[Medulla Oblongata|medulla oblongata]], and also blocks serotonin receptors in the chemoreceptor trigger zone. It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors.
===Muscarinic Receptor Antagonists===
===Muscarinic Receptor Antagonists===