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*Cause [[Peritoneal cavity - inflammatory#In dogs|peritonitis in dogs]] and [[Peritoneal cavity - inflammatory#In cattle|peritonitis in cattle]] and [[Peritoneal cavity - inflammatory#In pigs|peritonitis in pigs]]
*Cause [[Peritoneal cavity - inflammatory#In dogs|peritonitis in dogs]] and [[Peritoneal cavity - inflammatory#In cattle|peritonitis in cattle]] and [[Peritoneal cavity - inflammatory#In pigs|peritonitis in pigs]]
**Invasion causes an accute inflammatory response with many neutrophils
**Invasion causes an accute inflammatory response with many neutrophils
**Microabscesses are formed in the skin
**Microabscesses are formed in the skin
**Raised crusts develop in the affected regions
*Diagnosis:
**Giemsa-stained smears from scabs reveal branching filaments containing zoospores
**Immunofluorescence
**Scab material can be cultured on blood agar at 37 degrees centigrade, 2.5-10% carbon dioxide for 5 days
**Zoospores can be cultured
**After incubation, colonies are yellow and haemolytic (after 48 hours); they later become rough and yellow, and gain a mucoid appearance
**No growth on Sabouraud dectrose agar
*Clinical infections:
**Infection usually confined to epidermis
**Dermatophilosis
**Disease most prevalent in young animals
**Damage to the skin predisposes to infection; blood-sucking insects also thought to be involved in transmission
**Lesions after heavy rainfall predominantly affect dorsum of farm animals
**Papules, serous, exudative matting of hair, raised crusty scabs
**Scab formation more prominent in sheep and cattle than in horses
**Lesions may resolve within weeks if dry weather, or may progress
*Treatment:
**Parenteral antibiotics e.g oxytetracycline, pr penicillin-streptomycin combinations
*''Micropolyspora faeni and Thermactinomyces vulgaris'' in [[Bronchi and bronchioles - inflammatory#Extrinsic Allergic Bronchio-alveolitis|Bovine Farmers Lung]]
*''Thermactinomyces vulgaris'' may cause [[Bronchi and bronchioles - inflammatory#Chronic obstructive pulmonary disease (COPD)|COPD]]