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| <center><WikiQuiz | | <center><WikiQuiz |
| questionnumber="13" | | questionnumber="13" |
− | question="" | + | question="What next step do you propose?" |
− | choice1="" | + | choice1="Adjuvant doxorubicin chemotherapy to reduce the chance of development of pulmonary metastatic disease, followed by frequent checks for local recurrence (every 3 months for a year) and repeat radiographs at 6 and 12 months postoperatively. " |
− | choice2="" | + | choice2="Frequent checks for local recurrence (every 3 months for a year) and repeat radiographs at 6 and 12 months postoperatively. " |
− | choice3="" | + | choice3="Long-term piroxicam chemotherapy as an antiangiogenic treatment to reduce the development of pulmonary metastatic disease, as well as frequent checks for local recurrence (every 3 months for a year) and repeat radiographs at 6 and 12 months postoperatively." |
− | choice4="" | + | choice4="Adjuvant carboplatin chemotherapy to reduce the chance of development of pulmonary metastatic disease, followed by frequent checks for local recurrence (every 3 months for a year) and repeat radiographs at 6 and 12 months postoperatively." |
| choice5="" | | choice5="" |
− | correctchoice="4" | + | correctchoice="2" |
− | feedback1="" | + | feedback1="'''Incorrect'''. Adjuvant chemotherapy for grade 2 STS is not indicated, as there is no proven benefit, nor is it proven to be of benefit for grade 3 STS in dogs. Chemotherapy may have some value for highly anaplastic sarcomas, where immunohistochemistry is required to determine histiogenesis; however, even this is unproven. Choose again." |
− | feedback2="" | + | feedback2="'''Correct'''. Adjuvant chemotherapy is of no benefit for grade 2 STS, so should not be offered." |
− | feedback3="" | + | feedback3="'''Incorrect'''. Adjuvant chemotherapy for grade 2 STS is not indicated, and is likely to be of little benefit for grade 3 STS. It may have some value for highly anaplastic sarcomas, where immunohistochemistry is required to determine histiogenesis; however, even this is unproven. The chemotherapeutic agent with the most expected benefit is doxorubicin or similar, so this would be inappropriate therapy. Choose again." |
− | feedback4="" | + | feedback4="'''Incorrect'''. Adjuvant chemotherapy for grade 2 STS is not indicated, and is likely to be of little benefit for grade 3 STS. It may have some value for highly anaplastic sarcomas, where immunohistochemistry is required to determine histiogenesis; however, even this is unproven. The chemotherapeutic agent with the most expected benefit is doxorubicin or similar, so this would be inappropriate therapy. Choose again." |
| feedback5="" | | feedback5="" |
| image= ""> | | image= ""> |
| </WikiQuiz></center> | | </WikiQuiz></center> |