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Chlamydia and Chlamydophila species (view source)
Revision as of 09:08, 18 May 2008
, 09:08, 18 May 2008no edit summary
*May cause [[Joints - inflammatory#In Sheep|arthritis in sheep]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]]
*May cause [[Joints - inflammatory#In Sheep|arthritis in sheep]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]]
===Overview===
===Characteristics===
*Obligate intracellular bacteria
*Gram negative bacteria with outer membrane, LPS, ribosomes, DNA and RNA
*Peptidoglycan cell wall resistant to lysozyme
*Only grow in presence of living eukaryotic cells
*Unable to synthesis ATP therefore require intermediates from host cells
*
===Pathogenesis and pathogenicity===
*Elementary body, the infective form, phagocytosed and internalised into host epithelial cells
*Transformation into larger reticulate body
*Reticulate body divides by binary fission to form many new chlamydia cells
*Reticulate body has un-crosslinked peptidoglycan, which is cross-linked to form elementary bodies
*Elementary bodies released from dying host cells to infect other cells
===Clinical infections===
===Diagnosis===
===Treatments===