462
edits
Changes
Jump to navigation
Jump to search
no edit summary
*Exotoxins cause necrosis, haemolysis and death
*Exotoxins cause necrosis, haemolysis and death
*Collagenase, hyaluronidase and DNase enymes facilitate spread through tissues
*Collagenase, hyaluronidase and DNase enymes facilitate spread through tissues
===Neurotoxic clostridia===
**Rapidly fatal; anorexia, depression, fever
**Rapidly fatal; anorexia, depression, fever
*Causes [[General Pathology - Necrosis#Gas Gangrene|gas gangrene]] and [[Muscles - inflammatory#Gas gangrene|myositis]]
*Causes [[General Pathology - Necrosis#Gas Gangrene|gas gangrene]] and [[Muscles - inflammatory#Gas gangrene|myositis]]
* Causes [[General Pathology - Necrosis#Gas Gangrene|gas gangrene]] and [[Muscles - inflammatory#Gas gangrene|myositis]].
* Causes [[General Pathology - Necrosis#Gas Gangrene|gas gangrene]] and [[Muscles - inflammatory#Gas gangrene|myositis]].
*May be involved in [[Bacterial skin infections#Systemic bacterial infections|cutaneous lesions]]
*May be involved in [[Bacterial skin infections#Systemic bacterial infections|cutaneous lesions]]
*''Causes big head in rams - oedema of subcutaneous tissues of the head, neck and cranial thorax; necrotising lethal alpha toxin
*Causes big head in rams - oedema of subcutaneous tissues of the head, neck and cranial thorax; necrotising lethal alpha toxin
*Fluorescent antibody tests for histotoxic clostridia
*Fluorescent antibody tests for histotoxic clostridia
*ELISA, PCR for toxin detection
*ELISA, PCR for toxin detection
===Enteropathogenic and enterotoxaemic clostridia===
===Clostridium perfringens===
*[[General Pathology - Necrosis#Gas Gangrene|Gas gangrene]], ''C. perfringens'' type A:
**Extensive bacterial invasion of damaged muscle
**Gas production causing subcutaneous crepitus
**Similar manifestations as malignant oedema
*Necrotising enterocolitis in chickens and pigs
* Causes:
** [[Intestines - Fibrinous/ Haemorrhagic Enteritis#Lamb Dysentery (Enterotoxaemia with Blood)|Lamb dysentery]]
** [[Intestines - Fibrinous/ Haemorrhagic Enteritis#Colitis X|Colitis X]]
** [[Intestines - Catarrhal Enteritis#"Pulpy Kidney" Disease|Pulpy kidney disease]]
*** ''C. perfringens'' type D only.
** [[Peritoneal cavity - inflammatory#In cattle|Peritonitis in cattle]]
** [[Respiratory system - clinical signs#Dysphagia|Dysphagia in horses]]
** [[Muscles - inflammatory#Gas gangrene|Myositis]]