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Clostridium species (view source)

Revision as of 07:52, 26 May 2008

95 bytes added , 07:52, 26 May 2008

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*Exotoxins cause necrosis, haemolysis and death

*Collagenase, hyaluronidase and DNase enymes facilitate spread through tissues

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===Neurotoxic clostridia===

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**Rapidly fatal; anorexia, depression, fever

*Causes [[General Pathology - Necrosis#Gas Gangrene|gas gangrene]] and [[Muscles - inflammatory#Gas gangrene|myositis]]

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~~===Clostridium perfringens===~~

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*[[General Pathology - Necrosis#Gas Gangrene|Gas gangrene]]:

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**Extensive bacterial invasion of damaged muscle

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**Gas production causing subcutaneous crepitus

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**Similar manifestations as malignant oedema

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* Causes:

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** [[Intestines - Fibrinous/ Haemorrhagic Enteritis#Lamb Dysentery (Enterotoxaemia with Blood)|Lamb dysentery]]

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** [[Intestines - Fibrinous/ Haemorrhagic Enteritis#Colitis X|Colitis X]].

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** [[Intestines - Catarrhal Enteritis#"Pulpy Kidney" Disease|Pulpy kidney disease]]

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*** ''C. perfringens'' type D only.

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** [[Peritoneal cavity - inflammatory#In cattle|Peritonitis in cattle]]

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** [[Respiratory system - clinical signs#Dysphagia|Dysphagia in horses]]

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** [[General Pathology - Necrosis#Gas Gangrene|Gas gangrene]]

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** [[Muscles - inflammatory#Gas gangrene|Myositis]]

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* Causes [[General Pathology - Necrosis#Gas Gangrene|gas gangrene]] and [[Muscles - inflammatory#Gas gangrene|myositis]].

*May be involved in [[Bacterial skin infections#Systemic bacterial infections|cutaneous lesions]]

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*''Causes big head in rams - oedema of subcutaneous tissues of the head, neck and cranial thorax; necrotising lethal alpha toxin

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*Causes big head in rams - oedema of subcutaneous tissues of the head, neck and cranial thorax; necrotising lethal alpha toxin

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*Fluorescent antibody tests for histotoxic clostridia

*ELISA, PCR for toxin detection

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===Enteropathogenic and enterotoxaemic clostridia===

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===Clostridium perfringens===

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*[[General Pathology - Necrosis#Gas Gangrene|Gas gangrene]], ''C. perfringens'' type A:

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