*'''Status of target tissue''' - With overstimulation, target tissues hypertrophy, leading to increased functional tissue and an exaggerated response. Understimulation of target tissues leads to atrophy, resulting in less functional tissue and an inadequate response. | *'''Status of target tissue''' - With overstimulation, target tissues hypertrophy, leading to increased functional tissue and an exaggerated response. Understimulation of target tissues leads to atrophy, resulting in less functional tissue and an inadequate response. |