| + | The epidermis interfaces with the underlying dermis at the '''basement membrane zone (BMZ)'''. The binding includes anchoring junctions called ''hemidesmosomes'' and ''focal adhesions''. The former comprise ECM proteins such as '''laminin-5''' and '''type IV collage''' molecules, which form the lamina densa part of the BMZ. Collagen type VII is important in forming anchoring fibrils between the dermis and the basal lamina. |