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Chronic Immunemediated Superficial Keratoconjunctivitis (view source)
Revision as of 14:11, 27 February 2014
, 14:11, 27 February 2014Created page with "'''Chronic Immunemediated Superficial Keratoconjunctivitis''' is also known as '''Pannus''' or '''Chronic Superficial Keratitis'''. It is an immune-mediated condition, though ..."
'''Chronic Immunemediated Superficial Keratoconjunctivitis''' is also known as '''Pannus''' or '''Chronic Superficial Keratitis'''. It is an immune-mediated condition, though the aetilogy is not understood.
==Signalment==
Most common in '''German Shepherds''' and '''Greyhounds''', though any breed may be affected. More common in dogs exposed to high levels of '''ultraviolet radiation''', such as dogs living at high altitudes. Any age may be affected.
==Clinical Signs==
Signs are '''bilateral'''. Intially '''vascularisation''' of the cornea occurs with infiltration of '''plasma cells''' and '''lymphocytes'''. This progresses to '''thick granulation tissue''' on the surface of the cornea. There may also be '''depigmentation''' and '''thickening''' of the '''nictating membrane'''.
==Diagnosis==
'''Corneoconjunctival scrapings''' show large amounts of '''lymphocytes''' and '''plasmacytes'''.
==Treatment==
'''Topical''' [[Steroids]] and '''cyclosporine''' are used to control clinical signs, and should be tapered to the lowest dose needed. Minimising exposure to ultraviolet light may be helpful also.
==References==
Maggs, D et al (2007) '''Slatter's Fundamentals Of Veterinary Ophthalmology''' (Fourth Edition) ''Saunders''
Peiffer, Robert J, and Petersen-Jones, Simon M (2008) '''Small Animal Ophthalmology''' (Fourth Edition) ''Saunders''
[[Category:Corneal Diseases - Dog]]
==Signalment==
Most common in '''German Shepherds''' and '''Greyhounds''', though any breed may be affected. More common in dogs exposed to high levels of '''ultraviolet radiation''', such as dogs living at high altitudes. Any age may be affected.
==Clinical Signs==
Signs are '''bilateral'''. Intially '''vascularisation''' of the cornea occurs with infiltration of '''plasma cells''' and '''lymphocytes'''. This progresses to '''thick granulation tissue''' on the surface of the cornea. There may also be '''depigmentation''' and '''thickening''' of the '''nictating membrane'''.
==Diagnosis==
'''Corneoconjunctival scrapings''' show large amounts of '''lymphocytes''' and '''plasmacytes'''.
==Treatment==
'''Topical''' [[Steroids]] and '''cyclosporine''' are used to control clinical signs, and should be tapered to the lowest dose needed. Minimising exposure to ultraviolet light may be helpful also.
==References==
Maggs, D et al (2007) '''Slatter's Fundamentals Of Veterinary Ophthalmology''' (Fourth Edition) ''Saunders''
Peiffer, Robert J, and Petersen-Jones, Simon M (2008) '''Small Animal Ophthalmology''' (Fourth Edition) ''Saunders''
[[Category:Corneal Diseases - Dog]]