Changes

Amitriptyline also antagonises α2-adrenoceptors, which can also lead to agitation and tachycardia.

Amitriptyline also antagonises α2-adrenoceptors, which can also lead to agitation and tachycardia.

TCAs can also cause loss of libido [breeding animals] and mild corneal drying. They can cause galactorrhea through increased prolactin secretion [esp. cats].

TCAs can also cause loss of libido [breeding animals] and mild corneal drying. They can cause galactorrhea through increased prolactin secretion [especially in cats].

Finally, those TCAs that depend upon NorAdrenaline reuptake inhibition for a part of their effect are sometimes associated with explosive emotional reactions including aggression. They should be used with some care.

Finally, those TCAs that depend upon NorAdrenaline reuptake inhibition for a part of their effect are sometimes associated with explosive emotional reactions including aggression. They should be used with some care.