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Selective Serotonin Reuptake Inhibitors (Clomipramine, Fluoxetine) (view source)
Revision as of 13:08, 12 September 2014
, 13:08, 12 September 2014→Interactions
===Interactions===
===Interactions===
'''Care should be taken if used in conjunction with any of the following drugs, which may interact and cause adverse effects:'''
'''Care should be taken if used in conjunction with any of the following drugs, which may interact and cause adverse effects:'''
*Morphine: enhanced analgesia and respiratory depression.
*Opioids (e.g. morphine): enhanced analgesia and respiratory depression.
*MAOIs: risk of serotonin syndrome, advise washout period of 2-3 weeks between treatment with these drugs.
*MAOIs: risk of serotonin syndrome, advise washout period of 2-3 weeks between treatment with these drugs.
*Phenothiazines: increased shared adverse effects (CVS, etc), mutual increase in serum levels due to competition for cytochrome p450. Definite risk of severe adverse affects and toxicity.
*Phenothiazines: increased shared adverse effects (CVS, etc), mutual increase in serum levels due to competition for cytochrome p450. Definite risk of severe adverse affects and toxicity.