Although large amounts of magnesium are stored in bone, it is '''not readily mobilised''' as a reserve for the animal when the supply of dietary magnesium is insufficient. The absorption of magnesium is via an active transport process but passive diffusion from the digestive tract can occur if there is a concentration gradient from the gastrointestinal lumen to the extracellular space. Extracellular magnesium is vital for normal nerve function. A common sign of magnesium deficiency is hyperexcitability caused by a reduction in the resting potential of the nerve membrane, which allows the [[Sodium - Nutrition#Roles in the Body|action potential]] to be triggered prematurely.
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Although large amounts of magnesium are stored in bone, it is '''not readily mobilised''' as a reserve for the animal when the supply of dietary magnesium is insufficient. The absorption of magnesium is via an active transport process but passive diffusion from the digestive tract can occur if there is a concentration gradient from the gastrointestinal lumen to the extracellular space. Extracellular magnesium is vital for normal nerve function. A common sign of magnesium deficiency is hyperexcitability caused by a reduction in the resting potential of the nerve membrane, which allows the [[Neurons - Anatomy & Physiology#Nerve Impulse Propagation|action potential]] to be triggered prematurely.