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==Consequences of Biotin Deficiency==
 
==Consequences of Biotin Deficiency==
Naturally occurring biotin deficiencies have not been reported unless accompanied by the feeding of raw egg white. Egg white contains a compound called avadin, which irreversibly binds biotin, making it unavailable for physiologic use.
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Naturally occurring biotin deficiencies have not been reported unless accompanied by the feeding of raw egg white. Egg white contains a compound called [[Nutrition Glossary#Avadin|avadin]], which irreversibly binds biotin, making it unavailable for physiologic use.
 
====Dogs:====
 
====Dogs:====
 
Dogs fed raw egg white develop hyperkeratosis of the skin and scaling<ref name="NRC">National Research Council (NRC). Vitamins. In Nutrient Requirements for Dogs and Cats. 2006 Washington, DC: National Academies Press p.230-231.</ref>.
 
Dogs fed raw egg white develop hyperkeratosis of the skin and scaling<ref name="NRC">National Research Council (NRC). Vitamins. In Nutrient Requirements for Dogs and Cats. 2006 Washington, DC: National Academies Press p.230-231.</ref>.
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