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Monogastric Stomach - Anatomy & Physiology (view source)
Revision as of 08:08, 17 July 2008
, 08:08, 17 July 2008→Histology
*Chief (zygomatic) cells secreting pepsinogen
*Chief (zygomatic) cells secreting pepsinogen
**Secreted in response to vagus and gastrin
**Basophilic
**More abundant in base of glands
**Pepsinogen unfolds and cleaves itself (autocatalyses) in response to hydrochloric acid
**Only active in acidic envrionments
[[Image:Fundic region of glandular stomach.jpg|thumb|right|150px|Fundic Region of Glandular Stomach (Parietal and Chief cells)- Copyright RVC 2008]]
[[Image:Fundic region of glandular stomach.jpg|thumb|right|150px|Fundic Region of Glandular Stomach (Parietal and Chief cells)- Copyright RVC 2008]]
*Goblet cells secreting mucous
*Goblet cells secreting mucous
**Protects against autodigestion
*Parietal (oxyntic) cells secreting hydrochloric acid in gastric pits
*Parietal (oxyntic) cells secreting hydrochloric acid in gastric pits
**Aids digestion
**Activates gastric enzymes, e.g. pepsinogen to pepsin
**Kills microorganisms and enzymes that enter with food
**Secreted in response to vagus or pepsin
**Large, pyramid shaped
**More abundant in upper region of glands
*Gastrin from pyloric G cells
*Gastrin from pyloric G cells