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Spleen - Anatomy & Physiology (view source)
Revision as of 11:56, 17 July 2008
, 11:56, 17 July 2008→Vasculature
===Vasculature===
===Vasculature===
The splenic artery, a branch of the celiac artery, supplies the spleen. The artery branches into arterioles and capillaries, which may either:
<p>The splenic artery, a branch of the celiac artery, supplies the spleen. The artery branches into arterioles and capillaries, which may either:
*Connect with the venous sinuses, or
*Connect with the venous sinuses, or
*Terminate with open ends in the splenic cords.
*Terminate with open ends in the splenic cords
Blood released into the splenic cords, either from the sinuses or capillaries eventually filters back into the sinus network. The sinuses converge and empty into trabecular veins, which then merge into a single splenic vein which then empties into the portal vein.
Blood released into the splenic cords, either from the sinuses or capillaries eventually filters back into the sinus network. The sinuses converge and empty into trabecular veins, which then merge into a single splenic vein which then empties into the portal vein.</p>
<p>Lymphocytes in the arterial blood migrate from the red pulp sinuses, through the splenic cords and through the white pulp. T cells specifically migrate through the PALS and B cells specifically migrate through the follicles. Antigen in the blood is filtered by the large numbers of macrophages in the splenic cords and white pulp.</p>
Lymphocytes in the arterial blood migrate from the red pulp sinuses, through the splenic cords and through the white pulp. T cells specifically migrate through the PALS and B cells specifically migrate through the follicles. Antigen in the blood is filtered by the large numbers of macrophages in the splenic cords and white pulp.
====Species Differences====
====Species Differences====
The splenic artery:
<p>The splenic artery:
*Passes through the spleen without dividing in ruminants
*Passes through the spleen without dividing in ruminants
*Branches regularly as it passes through the spleen in horses and pigs
*Branches regularly as it passes through the spleen in horses and pigs
*Branches before it reaches the spleen in dogs and cats
*Branches before it reaches the spleen in dogs and cats</p>
===Innervation===
===Innervation===