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Spleen - Anatomy & Physiology (view source)
Revision as of 12:17, 17 July 2008
, 12:17, 17 July 2008→Species Differences
<p>White pulp is organised in relation to the splenic arterioles and consists of discrete lymphoid tissue surrounding a central arteriole. There is a sheath of T-cells directly around the arteriole, the periarteriolar lymphoid sheath (PALS), which is surrounded by a marginal sinus, and then a zone of B-cells and macrophages (the marginal zone). B cell follicles are associated with the marginal zone and expand and develop germinal centres after antigen activation. The marginal sinuses are linked to the red pulp sinuses. </p>
<p>White pulp is organised in relation to the splenic arterioles and consists of discrete lymphoid tissue surrounding a central arteriole. There is a sheath of T-cells directly around the arteriole, the periarteriolar lymphoid sheath (PALS), which is surrounded by a marginal sinus, and then a zone of B-cells and macrophages (the marginal zone). B cell follicles are associated with the marginal zone and expand and develop germinal centres after antigen activation. The marginal sinuses are linked to the red pulp sinuses. </p>
====Species Differences====
====Species Differences====
<p>The capsule and trabeculae are much more muscular in carnivores than ruminants</p>
<p>The capsule and trabeculae are much more muscular in carnivores and horses than ruminants</p>
*Carnivores
**Is elongated and dumb bell shaped (larger ventrally)
*Ruminants
**Is flat and oblong shaped
*Horses
**Lies under the last three ribs. Dorsally it is broad but narrows as it extends cranially and ventrally
*Pigs
**Elongated and strap like under the last few ribs
*Birds
**Lies alongside, to the right, of the proventriculus and is found caudaodorsally to the liver
**Spherical in chickens, triangular in ducks & oval in pigeons
===Vasculature===
===Vasculature===