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Bone Response to Damage
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Revision as of 10:24, 18 July 2008
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10:24, 18 July 2008
→Bone development
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****Used by surgeons to treat [[Bones - developmental#Angular limb deformity|angular limb deformities]]
****Used by surgeons to treat [[Bones - developmental#Angular limb deformity|angular limb deformities]]
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===Bone development===
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*Two main types of bone development:
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**'''Endochondral ossification''' (cartilage model)
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***Long bones mainly - physis and metaphysis
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***Mesenchymal cells differentiate into chondroblasts
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****Produce scaffold of mineralised cartilage on which osteoblasts deposit bone
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***Vascularised
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***Developed centres of ossification
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****Primary (diaphyseal)
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****Secondary (epiphyseal)
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**'''Intramembranous ossification'''
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***Flat bones mainly (e.g. skull), shaft of long bones
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***Mesenchymal cells differentiate into osteoblasts
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***No cartilage precursor template
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