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***Produced by <u>C-cells in the thyroid glands</u> in response to <u>increased</u> serum calcium
 
***Produced by <u>C-cells in the thyroid glands</u> in response to <u>increased</u> serum calcium
 
***Inhibits osteoclasts
 
***Inhibits osteoclasts
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===Bone dynamics===
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*Bone growth and maintenance of normal structure are directly related to mechanical forces
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*Mechanical forces generate bioelectrical potentials (piezoelectricity)
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**These potentials strengthen bone
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**Inactivity reduces the potentials -> bone loss
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*In neonates:
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**Bone growth predominates
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**Modelling is important
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*In adults:
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**Formation of bone is balanced by resorption - remodelling
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**Continues throughout life under the influence of hormones and mechanical pressure
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**Bone resorption may exceed formation in pathological states (hormonal, trauma, nutritional) or in old age and disuse
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<big><center>[[Bones|'''BACK TO BONES''']]</center></big>
 
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