Changes

The kidneys receive 25% of cardiac output. From this they filter 20% of the plasma forming a filtrate of which all but 1% is reabsorbed. This equates to the entire circulatory volume being filtered and reabsorbed every 30 minutes. The kidneys respond dynamically to changes in blood pressure and hydration status, using several mechanisms of [[Kidney Control of Blood Pressure - Anatomy & Physiology|regulation]] including the [[Renin Angiotensin Aldosterone System| Renin-Angiotensin-Aldosterone system]] which can alter the movement of sodium chloride and water in the vascular system and extracellular spaces.

The kidneys receive 25% of cardiac output. From this they filter 20% of the plasma forming a filtrate of which all but 1% is reabsorbed. This equates to the entire circulatory volume being filtered and reabsorbed every 30 minutes. The kidneys respond dynamically to changes in blood pressure and hydration status, using several mechanisms of [[Kidney Control of Blood Pressure - Anatomy & Physiology|regulation]] including the [[Renin Angiotensin Aldosterone System| Renin-Angiotensin-Aldosterone system]] which can alter the movement of sodium chloride and water in the vascular system and extracellular spaces.

The kidneys are responsible for the production and release of two [[Kidney Endocrine Function - Anatomy & Physiology|hormones]] - Erythropoietin, which is produced by a population of specialized fibroblasts in the renal cortex <ref>Lineage tracing analysis defines erythropoietin-producing cells as a distinct subpopulation of resident fibroblasts with unique behaviors

The kidneys are responsible for the production and release of multiple [[Kidney Endocrine Function - Anatomy & Physiology|hormones]], including Erythropoietin, which is produced by a population of specialized fibroblasts in the renal cortex <ref>Lineage tracing analysis defines erythropoietin-producing cells as a distinct subpopulation of resident fibroblasts with unique behaviors

Kaneko, Keiichi et al.

Kaneko, Keiichi et al.