Line 28: |
Line 28: |
| *Pastures can become heavily contaminated, leading to outbreaks | | *Pastures can become heavily contaminated, leading to outbreaks |
| *Transmission via inhalation of dust contaminated with ''R. equi'' | | *Transmission via inhalation of dust contaminated with ''R. equi'' |
| + | *Organisms survive inside cells |
| *Virulence associated with specific surface antigens encoded by a large plasmid | | *Virulence associated with specific surface antigens encoded by a large plasmid |
| *Capsular polysaccharide and mycolic acids in cell wall prevent phagocytosis | | *Capsular polysaccharide and mycolic acids in cell wall prevent phagocytosis |
| + | *Cell mediated response required to clear infection |
| | | |
| | | |
Line 35: |
Line 37: |
| | | |
| *[[Bacterial infections#Rhodococcus equi|Bronchoneumonia]] and lung abscessation in foals less than 4 months | | *[[Bacterial infections#Rhodococcus equi|Bronchoneumonia]] and lung abscessation in foals less than 4 months |
| + | *Infection associated with under-developed cell-mediated immunity |
| *Acute disease in 1 month-old foals: acute fever, anorexia, bronchopneumonia | | *Acute disease in 1 month-old foals: acute fever, anorexia, bronchopneumonia |
| *Insidious disease in 2-4 month-old foals with coughing, dyspnoea, weight loss, exercise intolerance, loud, moist rales on lung auscultation | | *Insidious disease in 2-4 month-old foals with coughing, dyspnoea, weight loss, exercise intolerance, loud, moist rales on lung auscultation |