Changes

**This causes preformed granules containing GLUT 4 receptors to be transported and expressed at the cell membrane.

**This causes preformed granules containing GLUT 4 receptors to be transported and expressed at the cell membrane.

**Cells can now take up glucose from the blood and store it as glycogen or fat.

**Cells can now take up glucose from the blood and store it as glycogen or fat.

*Increased glucose levels inside the cell increases the rate of glyogenesis and an increase in the rate of production of triacylglycerides.

*Increased glucose levels inside the cell increases the rate of glycogenesis and an increase in the rate of production of triacylglycerides.

*There is an increase in basal metabolic rate in other tissues.

*There is an increase in basal metabolic rate in other tissues.

**Insulin regulates the reaction in glycolysis where PEP is converted into pyruvate. This reaction is regulated by the enzyme pyruvate kinase. Insulin '''activates''' this enzyme by ''dephosphorylation'' via protein phosphatase 1 (PP1). This increases metabolism.

**Insulin regulates the reaction in glycolysis where PEP is converted into pyruvate. This reaction is regulated by the enzyme pyruvate kinase. Insulin '''activates''' this enzyme by ''dephosphorylation'' via protein phosphatase 1 (PP1). This increases metabolism.