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*Sight, smell, taste of food
 
*Sight, smell, taste of food
   −
*Vagus nerve (CN X)
+
*Vagus nerve ([[Nervous System - CNS - Anatomy & Physiology#Innervation - Cranial Nerves|CN X]])
 
**Parasympathetic fibres
 
**Parasympathetic fibres
 
**Synapse in submucosal plexus
 
**Synapse in submucosal plexus
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===Gastric===
 
===Gastric===
   −
*Chemical and mechanical receptors in stomach respond to stretch and chemical stimulation
+
*Chemical and mechanical receptors in [[Forestomach - Anatomy & Physiology|stomach]] respond to stretch and chemical stimulation
    
*Increase in pH of gastric contents
 
*Increase in pH of gastric contents
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*Response to undigested materials, especially proteins
 
*Response to undigested materials, especially proteins
   −
*Histamine and gastrin released
+
*Histamine and [[Endocrine System - Gut - Anatomy & Physiology|gastrin]] released
   −
*Negative feedback loop by sympathomimetic somatostatin released by paracrine method to inhibit gastrin secretion (when pH falls below 3)
+
*Negative feedback loop by sympathomimetic somatostatin released by paracrine method to inhibit [[Endocrine System - Gut - Anatomy & Physiology|gastrin]] secretion (when pH falls below 3)
    
*Submucosal and myenteric plexuses activated in vagus reflex arcs
 
*Submucosal and myenteric plexuses activated in vagus reflex arcs
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===Intestinal===
 
===Intestinal===
   −
*Chyme in the [[Duodenum - Anatomy & Physiology|duodenum]] inhibits acid secretion and motility by decreasing the stomach distension and increasing the stretch of the [[Duodenum - Anatomy & Physiology|duodenum]] leading to the enterogastric reflex
+
*Chyme in the [[Duodenum - Anatomy & Physiology|duodenum]] inhibits acid secretion and motility by decreasing the [[Forestomach - Anatomy & Physiology|stomach]] distension and increasing the stretch of the [[Duodenum - Anatomy & Physiology|duodenum]] leading to the enterogastric reflex
    
*A drop in pH below 4.5 causes release of secretin which inhibits parietal and chief cells and stimulate buffer release from the [[Pancreas - Anatomy & Physiology|pancreas]]
 
*A drop in pH below 4.5 causes release of secretin which inhibits parietal and chief cells and stimulate buffer release from the [[Pancreas - Anatomy & Physiology|pancreas]]
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