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The lifespan of bacteria differs from that of viruses in that it includes a '''colonization''' phase, which occurs on epithelial surfaces.  As bacteria are capable of self-replication (i.e. they don't require host cellular machinery), this colonization phase allows them to develop a highly skilled and lethal army before invading the body.  Once invasion occurs, spread can occur via the vascular or lymphatic systems.  The pathogenesis of a particular strain of bacteria very much depends upon its location in the body: "''Streptococcus pneumoniae'' in the lung causes pneumonia...whereas in the blood it causes a rapidly fatal systemic illness, pneumoncoccal sepsis." (Murphy, et al, 43)
 
The lifespan of bacteria differs from that of viruses in that it includes a '''colonization''' phase, which occurs on epithelial surfaces.  As bacteria are capable of self-replication (i.e. they don't require host cellular machinery), this colonization phase allows them to develop a highly skilled and lethal army before invading the body.  Once invasion occurs, spread can occur via the vascular or lymphatic systems.  The pathogenesis of a particular strain of bacteria very much depends upon its location in the body: "''Streptococcus pneumoniae'' in the lung causes pneumonia...whereas in the blood it causes a rapidly fatal systemic illness, pneumoncoccal sepsis." (Murphy, et al, 43)
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==Prevention and control==
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==Immunity to Bacteria==
 
*Bacterial evasion of immunity
 
*Bacterial evasion of immunity
 
**Bacterial capsules can avoid phagocytosis and complement activation
 
**Bacterial capsules can avoid phagocytosis and complement activation
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Phagocytosis and digestion are the primary tools of the Immune System to conquering bacterial infection.  These are enhanced by the production of [[Immunoglobulin G - WikiBlood|IgG]] and CD8+ Tcells, as well as by [[Complement - WikiBlood|complement]] activation.
 
Phagocytosis and digestion are the primary tools of the Immune System to conquering bacterial infection.  These are enhanced by the production of [[Immunoglobulin G - WikiBlood|IgG]] and CD8+ Tcells, as well as by [[Complement - WikiBlood|complement]] activation.
 
*[[Innate Immune System - WikiBlood#Innate Immunity to Bacteria|Innate Immunity to Bacteria]]
 
*[[Innate Immune System - WikiBlood#Innate Immunity to Bacteria|Innate Immunity to Bacteria]]
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==Prevention and control==
    
=[[Parasites - WikiBlood|Parasites]]=
 
=[[Parasites - WikiBlood|Parasites]]=
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