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Neurogenesis - Anatomy & Physiology (view source)
Revision as of 16:57, 26 August 2008
, 16:57, 26 August 2008→Neural Crest
**This contact causes cells of the crest neuroectoderm to undergo an epithelial to mesenchymal transition.
**This contact causes cells of the crest neuroectoderm to undergo an epithelial to mesenchymal transition.
**Cells that undergo this transition break away from the neuroectoderm and are called '''neural crest cells'''.
**Cells that undergo this transition break away from the neuroectoderm and are called '''neural crest cells'''.
*The peripheral nervous system (PNS) develops from the neural crest.
*'''The peripheral nervous system (PNS) develops from the neural crest.'''
*The undifferentiated neural crest cells migrate away from the neural tube along
*The undifferentiated neural crest cells migrate away from the neural tube along "pathways".
*These pathways are governed by repulsive cues from other cells, as well as proliferation and survival signals.
*They differentiate once they reach their destination.
*Other non - neural tissues also develop from the neural crest. The type of tissue that neural crest forms is dependant on the origination of the cell along the anterior - posterior axis:
::'''Anterior Neural Crest''' forms; sensory neurones and schwann cells; bones of the head; dermis of the face; and cartilage.
::'''Trunk Neural Crest''' forms; sensory neurones of the somatic and autonomic nervous systems (ANS); sympathetic motor neurones of the ANS; melanocytes.
::'''Posterior Neural Crest''' forms parasympathetic motor neurones of the gut, which control peristalsis.