<p>The lymph nodes are [[Secondary Lymphoid Tissue - Anatomy & Physiology|secondary lymphoid tissue]], and as the [[Spleen - Anatomy & Physiology|spleen]] removes antigens from the blood, lymph nodes remove antigens from tissue/lymph. Antigen presenting cells ([[Blood Vessels - WikiBlood#B cells|B cells]] and [[Blood Vessels - WikiBlood#T cells|T cells]]) migrate from peripheral tissue via afferent [[Lymphatic Vessels - Anatomy & Physiology|lymphatic vessels]] to the lymph nodes where they present their antigen to lymphocytes. [[Blood Vessels - WikiBlood#B cells|B cells]] and [[Blood Vessels - WikiBlood#T cells|T cells]] enter via the high endothelial venules by diapedesis and [[Blood Vessels - WikiBlood#B cells|B cells]] migrate to the cortex while [[Blood Vessels - WikiBlood#T cells|T cells]] to the deep cortex.</p>
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<p>The lymph nodes are [[Secondary Lymphoid Tissue - Anatomy & Physiology|secondary lymphoid tissue]], and as the [[Spleen - Anatomy & Physiology|spleen]] removes antigens from the blood, lymph nodes remove antigens from tissue/lymph. Antigen presenting cells ([[Lymphocytes - WikiBlood#B cells|B cells]] and [[Lymphocytes - WikiBlood#T cells|T cells]]) migrate from peripheral tissue via afferent [[Lymphatic Vessels - Anatomy & Physiology|lymphatic vessels]] to the lymph nodes where they present their antigen to lymphocytes. [[Lymphocytes - WikiBlood#B cells|B cells]] and [[Lymphocytes - WikiBlood#T cells|T cells]] enter via the high endothelial venules by diapedesis and [[Lymphocytes - WikiBlood#B cells|B cells]] migrate to the cortex while [[Lymphocytes - WikiBlood#T cells|T cells]] to the deep cortex.</p>
<p>Antibodies and immunologically competent cells leave the lymph nodes via the efferent lymphatics.</p>
<p>Antibodies and immunologically competent cells leave the lymph nodes via the efferent lymphatics.</p>