The kidneys work with the respiratory system to regulate H<sup>+</sup>. Where as the respiratory systems quickly compensates for a problem its is left to the kidneys to actually remove the problem and restore a proper balance. They do this by altering the plasma concentration of HCO<sub>3</sub><sup>-</sup>. | The kidneys work with the respiratory system to regulate H<sup>+</sup>. Where as the respiratory systems quickly compensates for a problem its is left to the kidneys to actually remove the problem and restore a proper balance. They do this by altering the plasma concentration of HCO<sub>3</sub><sup>-</sup>. |