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| ==Primary Immunodeficiency== | | ==Primary Immunodeficiency== |
| | | |
− | ===Deficiency of Innate Immunity=== | + | ===Deficiencies of Innate Immunity=== |
| | | |
− | ===Primary B Cell Deficiency===
| + | *Canine Cyclic Haematopoiesis |
| | | |
− | ===Primary T Cell Deficiency=== | + | *Canine Leukocyte Adhesion Deficiency (CLAD) |
| + | |
| + | *Bovine Leukocyte Adhesion Deficiency (BLAD) |
| + | |
| + | ===Deficiencies of Adaptive Immunity=== |
| + | |
| + | *Equine & Canine Severe Combined Immune Deficiency (SCID) |
| + | |
| + | *Selective IgA deficiency of German Shepherd Dogs |
| + | |
| + | *Immunodeficiency of Weimaraners |
| + | |
| + | *Rhinitis/Bronchopneumonia in Irish Wolfhounds |
| + | |
| + | *Pneumocystis infection in Miniature Dachshunds |
| | | |
| ===Severe Combined Deficiency=== | | ===Severe Combined Deficiency=== |
| + | |
| + | *Severe Combined Immune Deficiency(SCID) |
| + | **No functional B or T cells |
| + | |
| + | *Arthymic nude mice (no thymus) |
| + | **No functional T cells |
| + | |
| + | *Knock-out muce |
| + | **E.g. Gene coding for CD4, CD8, IL-10 removed |
| | | |
| ==Secondary Immunodeficiency== | | ==Secondary Immunodeficiency== |
| + | |
| + | ===Viral Causes=== |
| + | |
| + | *Feline Leukaemia Virus (FeLV) |
| + | |
| + | *Feline Immunodeficiency Virus (FIV) |
| + | |
| + | *Bovine Immunodeficiency Virus (BIV) |
| + | |
| + | ===Toxic Causes=== |
| + | |
| + | *Poisons |
| + | |
| + | ===Iatrogenic Causes=== |
| + | |
| + | *Drugs |
| + | **Corticosteroids |
| + | **Ciclosporin |
| + | **Cytoxic cancer therapy |
| + | |
| + | ===Other Causes=== |
| + | |
| + | *Malnutrition |
| + | |
| + | *Chronic disease |
| + | |
| + | *Stress |
| + | |
| + | *Senescence |
| | | |
| ==Links== | | ==Links== |