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* Thus, more LH and FSH are produced until puberty is reached.
 
* Thus, more LH and FSH are produced until puberty is reached.
   −
== The Influence of Blood Glucose and Fatty Acids ==
+
= The Influence of Blood Glucose and Fatty Acids =
    
* There are three types of presynaptic neurons that can stimulate GnRH neurons:
 
* There are three types of presynaptic neurons that can stimulate GnRH neurons:
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** Fatty acid sensitive neurons
 
** Fatty acid sensitive neurons
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=== Leptin ===
+
== Leptin ==
    
* Leptin is a hormonal peptide produced by adipocytes (fat cells).
 
* Leptin is a hormonal peptide produced by adipocytes (fat cells).
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* Leptin may be a signal that notifies GnRH neurons directly that nutritional status is adequate because a threshold 'fatness' has been achieved. Leptin may also signal to GnRH neurons indirectly via stimulation of neuropeptide Y, which in turn stimulates GnRH neurons.
 
* Leptin may be a signal that notifies GnRH neurons directly that nutritional status is adequate because a threshold 'fatness' has been achieved. Leptin may also signal to GnRH neurons indirectly via stimulation of neuropeptide Y, which in turn stimulates GnRH neurons.
   −
=== Glucose ===
+
== Glucose ==
    
* Blood glucose stimulate glucose sensing neurons.
 
* Blood glucose stimulate glucose sensing neurons.
 
* Glucose sensing neurons stimulate GnRH neurons to produce GnRH.
 
* Glucose sensing neurons stimulate GnRH neurons to produce GnRH.
   −
=== Blood Fatty Acids ===
+
== Blood Fatty Acids ==
    
* Blood fatty acids stimulate neurons that in turn stimulate GnRH neurons.
 
* Blood fatty acids stimulate neurons that in turn stimulate GnRH neurons.
 
* Blood fatty acids are an indicator of nutritional status.
 
* Blood fatty acids are an indicator of nutritional status.
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