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* Larger and larger quantities of testosterone and oestradiol are needed to inhibit the GnRH neurons.
 
* Larger and larger quantities of testosterone and oestradiol are needed to inhibit the GnRH neurons.
 
* Thus, there is decreased sensitivity to the negative feedback of testosterone/oestrodiol.
 
* Thus, there is decreased sensitivity to the negative feedback of testosterone/oestrodiol.
* Therefore, the hypothalamus can produce increasing amounts of GnRH.
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* Therefore, the [[Hypothalamus_-_Anatomy_%26_Physiology|hypothalamus]] can produce increasing amounts of GnRH.
 
* Thus, more LH and FSH are produced until puberty is reached.
 
* Thus, more LH and FSH are produced until puberty is reached.
  
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