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Major Histocompatability Complexes (view source)
Revision as of 12:45, 9 September 2008
, 12:45, 9 September 2008→The Genetics of the MHC
* There are millions of variations in antibodies and TCR
* There are millions of variations in antibodies and TCR
** However, with MHC there is very limited variation between molecules
** However, with MHC there is very limited variation between molecules
*Allelic variation within the MHC molecule occurs at the peptide binding site and on the top or sides of the binding cleft
* MHC polymorphism has been best studied in the human
* MHC polymorphism has been best studied in the human
[[Image:Location of Polymorphic Residues 2.jpg|thumb|right|150px|Location of Polymorphic Residues - Copyright Prof Dirk Werling DrMedVet PhD MRCVS]]
[[Image:Location of Polymorphic Residues 2.jpg|thumb|right|150px|Location of Polymorphic Residues - Copyright Prof Dirk Werling DrMedVet PhD MRCVS]]