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T cell differentiation (view source)
Revision as of 13:36, 9 September 2008
, 13:36, 9 September 2008→Antigen Presentation by Dendritic Cells
*Veiled cells enter the paracortical region of the [[Lymph Nodes - Anatomy & Physiology|lymph node]] where they present antigen to [[Lymphocytes - WikiBlood#T cells|T cells]]. They are now called '''Interdigitating Dendritic Cells'''
*Veiled cells enter the paracortical region of the [[Lymph Nodes - Anatomy & Physiology|lymph node]] where they present antigen to [[Lymphocytes - WikiBlood#T cells|T cells]]. They are now called '''Interdigitating Dendritic Cells'''
'''Dendritic Cells'''
*There are two different lineages of dendritic cells:
*There are two different lineages of dendritic cells:
**From myeloid precursor cells
**From myeloid precursor cells
**From plasmacytoid precursor cells
**From plasmacytoid precursor cells
*Stimulate a primary T cell response
*Migrate through tissues, track to [[Lymphocytes - WikiBlood#T cells|T cells]] dependent areas of [[Lymph Nodes - Anatomy & Physiology|lymph node]] and cluster with [[Lymphocytes - WikiBlood#T cells|T cells]]
*Dendritic cells have unique capabilities to take up antigen by pathways involving phagocytosis, macropinocytosis and clathrin-coated pits
*Cell-surface antigen phenotype distinguishing it from monocytes/macrophages and [[Lymphocytes - WikiBlood#B Cells|B cells]]
*Cell-surface expression pattern according to their differentiation/maturation/activation
*Main function is priming of [[Lymphocytes - WikiBlood#T cells|T helper cells]]
==TH<sub>1</sub> Cells==
==TH<sub>1</sub> Cells==