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* Regulatory T cells are unique in their use of a transcription repressor known as FoxP3
* Regulatory T cells are unique in their use of a transcription repressor known as FoxP3
** Encoded by a gene on the X chromosome, rare deficiencies in FoxP3 are characterised by autoimmunity, primarily towards gut tissue, the thyroid, pancreative beta-cells and the skin. Sufferers are unable to produce regulatory T cells and the only known treatment is a bone marrow transplant from a MHC-identical sibling.
** Encoded by a gene on the X chromosome, rare deficiencies in FoxP3 are characterised by autoimmunity, primarily towards gut tissue, the thyroid, pancreative beta-cells and the skin. Sufferers are unable to produce regulatory T cells and the only known treatment is a bone marrow transplant from a MHC-identical sibling.
==[[Host invasion by microorganisms flashcards- Wikiblood|Host invasion flashcards]]==