These hormones function as male sex hormones. The most important of these is '''testosterone'''. This is produced by the conversion of pregnenolone to dehydroepiandrosterone, then to androstenedione and finally to testosterone. This occurs in the zona reticularis. They bind in the blood to sex hormone-binding globulin (SHBG) and albumin. Most adrenal androgens have little physiological action untill they are coverted to testosterone.
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They have little importance within the male. In women adrenal androgens, which are converted to oestrogen in adipose tissue, is the most important source of oestrogen after the menopause.